The use of impotence injections as a successful treatment for male impotence began in the early 1990's.

Papaverine, a drug originally used to dilate blood vessels during surgery and to assist patients with blood circulation problems, was found to produce erections when injected directly into the penis.

Male impotence (or erectile dysfunction) is defined as the inability to achieve or maintain an erection sufficient for sexual intercourse, and includes the inability to get an erection as a result of sexual stimulation or to lose your erection prior to ejaculation.

The physical and psychological processes involved in creating an erection are numerous. If one of these processes fails, the result is impotence.

Drugs such as papaverine, when used in impotence injections, dilate and relax the blood vessels and enable the penis to engorge with blood, thereby creating an erection.

Advancements in drug therapies to treat male impotence have led to a variety of active ingredients now being used in impotence injections, either individually or in combination.

The most commonly used drug for the treatment of male impotence is alprostadil, a synthetic form of prostaglandin, which is a hormone found naturally in the body.

When prostaglandin is used in combination with papaverine and phentolamine, the overall effectiveness of the treatment increases by 50% to 60%. This combination of drugs is often referred to as tri-mix.

Impotence injections reportedly produce successful erections in over 95% of cases. This form of treatment appears to work regardless of whether there is a physical or psychological cause for male impotence.

The Facts About Impotence Injections

• Impotence medications administered by injection must be prescribed by a doctor. Your doctor will determine the correct combination of drugs, the dosage required and the proper method for injection.

• The initial impotence injection will usually be administered by your doctor to demonstrate the procedure to you, view the reaction and determine the correct dosage.

  An instructional booklet or pamphlet, preferably with explanatory diagrams, will usually be given to you to ensure that the injections are correctly administered.

• The injections are made using a very fine needle and syringe - usually the same size as those used by diabetics for insulin injections - and are considered to be painless.

• Inside the penis are two chambers called the corpora cavernosa. These chambers are filled with spongy tissue and run the length of the penis. The impotence injection is made directly into the corpora cavernosa. Care should be taken to ensure that you don't inject directly into the urethra.

• The doctor will explain to you that the dosage may be adjusted slightly upwards or downwards depending on the circumstances and your state of health. The appropriate dosage should enable you to achieve an erection that lasts anywhere between 60 minutes and a maximum of 90 minutes.

• The medication generally starts to produce an erection within 10 to 15 minutes.

Impotence Injection Precautions

• Medical experts suggest that you don't use impotence injections more than three times a week.

• You SHOULD NOT use impotence injections if you have any of the following conditions:
  • where there is a health risk if you engage in sexual activity
  • allergic reaction to alprostadil
  • any deformity of the penis (Peyronie's Disease, cavernosal fibrosis or angulation)
  • sickle cell anemia
  • leukemia (cancer of the blood cells)
  • multiple myeloma (cancer of the bone marrow)

Possible Side Effects With Impotence Injections

• One of the most frequently reported side effects of impotence injections is priapism. This is a medical condition where the penis remains erect for a prolonged period of time. Priapism if often the result of using a higher dose of medication than is required.

  If your penis remains erect for over two hours, or becomes painful, seek medical attention immediately.

• Scarring (fibrosis) is possible as a result of long-term use. However, medical reports have shown that some men have used impotence injections for many years with no adverse effects. The best way to avoid scarring is to inject into different areas of the penis.

• Some men have reported pain in their penis and testicles following the injection, but this is usually mild and disappears quickly.

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